This panel explores the foundational elements of an innovation ecosystem that harnesses the full potential of technology advancements such as AI, to address pressing challenges in agrifood systems and climate resilience. To unlock technology's transformative power, innovation ecosystems need to integrate demand-driven problem identification, robust R&D, inclusive partnerships, and scalable pathways for investment and impact. Panelists from tech companies, R&D institutions, investment bodies, UN and development organizations discuss the specific components required to create an adaptive, resilient ecosystem capable of producing sustainable solutions to current and future global challenges.